Understanding of bone marrow
What is bone marrow? It is located? Marrow will hurt body? Bone marrow is the hematopoietic tissue in the body, located within the body's many bones, it is responsible for manufacturing red blood cells, white blood cells, platelets and other blood cells, apart from the ongoing differentiation and maturation, to supplement the body's blood loss, the bone marrow itself is damaged (such as down injury, fractures, bone marrow will detract from) also regeneration. And if the abnormal bone marrow cells can lead to such as leukemia, aplastic anemia and other blood diseases.
Many people will be the bone marrow and spinal cord fluid (commonly known as the keel water) mixed, in fact, refers to the spinal fluid in the spinal cord surrounded by a thin layer of water outside, nothing to do with the bone marrow, and spinal fluid is only one of the body fluid metabolism continuously , usually to do lumbar puncture, pumping water, check the keel encephalitis, meningitis, etc., is quite common for a hospital examination, would not have any damage.
"What is bone marrow transplantation"
The so-called bone marrow transplant is taken from a healthy donor bone marrow cells within, loading bags, again the same as blood transfusion, injection method to drip into the patient. The following is from the donor and the marrow of those affected by surgical methods:
From the donor bone marrow method:
Marrow from the donor should take one to two weeks before surgery to receive a complete and detailed medical examination.
In the donor bone marrow in the seven days prior to the respective graft blood banks collected two hundred and fifty to five hundred cc of blood, the first store.
Bone marrow impose the same day in the operating room under general anesthesia, by a specialist physician with a special needle and syringe, since from the donor at the hip to extract the required on both sides of the iliac bone marrow fluid (about one to three hours), injected into the blood bag. The amount collected by those affected by spinal cord depending on body weight, about 500 to 1000 cc or so.
To the prior existence of bone marrow from the donor transferred back up the body, to supplement the blood loss during marrow volume.
Marrow obtained after surgery, in general, can be discharged the next day.
Who received marrow transplants by the method: (to leukemia as an example)
About two weeks before the transplantation of patients must be into the sterile room, first with high doses of chemotherapy and radiation, all of the bone marrow cells the patient, regardless of good or bad completely destroyed in order to thoroughly bad quality, elimination of diseased cells ( This called Repentance off therapy); the other hand, this also excluded the role of inhibition in order to facilitate regeneration of allogeneic bone marrow differentiation in a patient. At this point the patient is fragile and dangerous condition, require careful care, waiting for the implantation of healthy bone marrow, in order to avoid bleeding, severe infections and other dangerous conditions.
Transplant day, the HLA matching donor who matches out of volunteer bone marrow stored in bags and then by drip injection, about two to four hours into the patient.
After transplantation, the patient must live in the sterile room a few weeks time, careful attention is the possibility of rejection or infection, or other symptoms. After about two weeks to see signs of a successful transplant. First of all, increase the amount of white blood cells is bone marrow transplantation to create new blood in the first message. White blood cell count will continue to rise, and then produce new platelets and red blood cells, when transplanted bone marrow began to function, you can go to the general ward. Can return to society after discharge and to restore normal life for learning.
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