Leukemia bone marrow transplant

Autologous bone marrow transplantation points and allograft transplantation, autologous transplantation is the disease most patients will relapse. Present theory can cure leukemia, allogeneic transplant, much of the information or drama or media reports, so that people mistakenly believe that bone marrow transplant is the only option for cure of leukemia, it is not.

Allogeneic hematopoietic stem cell transplantation for certain blood diseases or even the only radical method of treatment. However, stem cell transplantation is not 100% successful, allogeneic hematopoietic stem cell transplantation transplantation-related mortality, there is a certain recurrence rate. Transplant units in different transplant models because of different effects are also different. Also due to the specific circumstances of different patients with different risk and efficacy. Transplant goal is to cure disease, but also taking a big risk. No matter the outcome, to pay a higher price. And once pretreatment, there is no way to undo and go back in the. Therefore, patients should weigh when making decisions, and make full preparations and prepared for the economic. Some patients, such as frail, poor physical condition, or is itself a continuing remission relapsed or refractory acute leukemia, or economic conditions were not too abundant, the decision must consult a professional before transplantation blood disease specialists,

1. To find matching bone marrow, which can be unrelated donor (more difficult), relatives (parents, brothers and sisters) or their own (autologous transplantation)
2. For transplant preparation, such as physical examination, chemotherapy, and doctors to develop the program, buy some warehouse supplies, and more!
3. Into the graft position, bigger doses of chemotherapy, the WBC hit close to zero, and then back to the input provided for the bone marrow, waiting for the value of living bone marrow, the indicators were normal, only the position! (From the depot to a warehouse, about one to two months, if no conditions would occur)
4. A position to continue to stay in hospital after observation and prevention of severe rejection!


An organ transplant, the patients with normal bone marrow in vivo by the intravenous infusion to replace the treatment of bone marrow lesions. For the treatment of hematopoietic function abnormalities, immune dysfunction, hematological malignancies and other malignancies. With this therapy can improve efficacy, improve outcomes, have long survival and even cure.
Are now doing with the technology development of peripheral blood transplantation. Not taken donor bone marrow, which is more secure and easy.
Bone marrow transplant success rate is affected by many factors and the test of time, usually go through five checkpoints: 1, off chemotherapy before transplantation. 2, 3, transplant related, immune rejection after transplantation off. 4, 5 off infection, transplant related chemotherapy. Only turn passed over the five tests, and genetic testing made after six months, the patient's body found in gene expression for the marrow, and bone marrow, blood and major organs were normal, no obvious symptoms, be considered truly successful. Some common clinical transplant patients after extravehicular January, March, June or even a year after the recurrence. This type of patient condition, body organ function, autoimmunity, transplantation complications and the process for pulp and patient matching loci in line rate, the overall level of transplant centers have a significant relationship. Transplanted bone marrow transplantation is currently the real news media report the success rate of 50%, but the medical profession recognized by 33% or so. Or 1 / 3, 1 / 3, 1 / 3 point of view: 1 / 3 patients in the transplant failed; 1 / 3 relapse within six months after transplantation; 1 / 3 of patients have transplant success.
Now the proportion of graft failure in decline, the general recurrence within a year also fell short, in mature, many of them are life-threatening infection and rejection is very unfortunate.


3:00 my sister did the day before yesterday, the death certificate is written in the graft-versus-host disease, hey my family to wear the dress, Cana, who are all bleeding points, so do not be too optimistic, to shun patients with heart it, eat, when to eat.