The benefits and disadvantages of renal transplantation?

Consider a kidney transplant
But the fear of risks
If you do go on dialysis has been
Renal transplantation done to seek suggestions
In the end or not to transplant?
After transplantation can live like a normal person?
How long that will use the bad kidney? I'm afraid of is that bad for a year later, and if by that time the money was gone too dialysis ..

Questions added:

There is a relative to donate the kidney if the words are not just need surgery just fine?

Best answer

Hello, I suggest you best kidney transplant, I have personally experienced, you can work even after a kidney transplant, as long as you cherish, take good care of the kidney, preferably with relatives, the success rate is very high, And eat less medication after surgery, dialysis, have 400 or so it once, and you would if a regular dialysis is necessary to 2,3 times a week, but also a lot of money, you change the kidney, much less by the crime, ah, you Do not listen to other people to save money, said first trace analysis, trace analysis of a week before you and a few days time to make money! And dialysis on the body is very good! Bad for the heart, and the longer the dialysis, the worse the body! I have personal experience, I am a long time because of dialysis, once into the emergency room, before deciding on a kidney transplant, your body will change day to day after renal good.

Do not know what you need transplants kidney transplantation is relative to you, or in the hospital waiting renal transplantation, if the former, then the risk to not be significant because family members living under normal circumstances 98 per cent transplantation success, if it is risk of renal transplantation in a slightly larger, but also more than 90 percent, and now our technology is very mature. The so-called renal transplantation and dialysis comparison is their pros and cons, and kidney transplantation has the advantage of improved quality of life, which can live like a normal person, but requires a lot of medication, drug prices are relatively higher for hemodialysis, As to how long it would use the bad kidney, it depends on the extent and maintenance of your own luck, and most likely a year to bad only a few percent, the price of kidney transplantation is still relatively high, generally if it is cadaveric renal transplants need the cost of 10 million, if you finish on the money renal transplant dialysis, and I still do not think you do, you can make money while dialysis side, until the economy allowed to conduct kidney transplant. Maybe I'm just saying maybe, after the science developed, you can use the cloned animals, the kidney transplant. If only you only need to pay relatives of transplant surgery costs can, of course, ah, what the cost of surgical treatment, if you have access to health care can be catastrophic if aid reimbursement, but the kidney transplant to give you all the costs that families can only privately can not be reimbursed

Two advantages of kidney transplantation
First, the long-term hemodialysis is not only costly, but will lead to a variety of other complications, can be compared with the dialysis uremic kidney transplant patients to save a more effective treatment, is currently the Western most effective treatment for kidney disease a treatment.
Second, after renal transplantation, due to rapid recovery of renal function, eliminating the pain of dialysis, diet without too many restrictions than before, which improves the quality of life, but also improve the ability to work and sexual life, increase the chance of pregnancy, a fundamental uremic symptoms under control.
Disadvantages of the six renal transplant
First, the complications of renal transplantation
(1) infection: transplant recipients are prone to infection because: ① patients suffered a large blood vessels and urinary tract surgery, a temporary decrease in resistance; ② inherent in uremic patients with decreased immunity; ③ immunosuppressive drugs applications, the common site of infection are: lung infection, urinary tract infections, wound infections.
(2) cardiovascular complications: cardiovascular complications after renal transplantation is the second leading cause of death. Including hypertension, heart failure, hyperlipidemia and so on.
(3) digestive complications include: abnormal liver function, upper gastrointestinal bleeding and acute pancreatitis.
(4) the endocrine and metabolic abnormalities: including hypercalcemia, hypophosphatemia, renal dysfunction, diabetes, hyperuricemia, bone disease, sexual dysfunction.
(5) the blood system complications: polycythemia, blood rheology changes (patients with different degrees of increased whole blood viscosity and plasma viscosity increases), bone marrow suppression.
(6) tumor: tumors in patients after renal transplantation the incidence of about 2% to 25%, tumors 3 sources: ① from the kidney (renal cell carcinoma, metastasis to the kidney tumor), rare; ② surgery recipients pre-existing tumor recurrence; ③ new onset of tumors. The latter is very common.
(7), the recurrence of kidney disease: occurrence of renal transplant kidney after renal transplantation, there are three sources: ① pre-existing kidney disease, mostly IgA nephropathy, such cases are rare; ② new and different with the primary disease occurred in kidney disease such as infection of glomerular disease, membranous nephropathy, focal segmental renal disease; ③ recurrence of primary disease, more common.
Second, the long-term survival of low
To carry out the first kidney transplant in China, but also a more mature technology. Although renal transplantation has been very satisfactory curative effect, the average survival rate of 94% a year or more, but in the long run, the effect is not satisfactory, and died of renal function in patients with more and more deaths than the kidney transplant for 40%. If renal function purely from the point of view, the operation is undoubtedly successful, but if the patient finally died, no matter what the reasons are, these transplants seem to have lost its meaning. At present, most medical institutions will focus attention in the preoperative donor and above the success rate of surgery on long-term survival after transplantation of organs and the survival rate of generally low quality of the cognitive. Accepted in many organ transplant patients, their long-term survival in the end how much they accept the quality of life after organ transplantation have improved much? Can come to the medical data is almost rare.
Present threat of long-term survival of renal transplant patients the main problem is drug toxicity, cardiovascular disease, viral infection, rejection, and the patient can not follow the doctor's guidance of long-term adherence, and poor compliance. Despite progress in recent years, anti-rejection drugs to kidney transplant patients greatly improved survival rates, but compared with the transplant surgery itself and postoperative medical care, rational drug use, diet exercise and living habits are equally important.
Clinically, the infection after transplantation has become the most important faced by doctors and patients, especially post-transplant CMV infection. Global data, 50% of patients after transplantation CMV infection occurs. Domestic migration statistics from the database results, the detection of CMV infection rate increasing, single-kidney transplant last year, 21% of patients have had infections after transplantation. Also symptomatic CMV infection in renal transplantation, liver transplantation, heart transplantation and heart - lung transplantation in the incidence rates were 8%, 29%, 25% and 39%. If after transplantation, CMV infection occurs, can lead to many serious consequences, such as increasing the incidence of acute and chronic rejection, cardiovascular disease, the incidence of diabetes after transplantation to reduce long-term survival and so on.
Cardiovascular disease is life-threatening kidney transplant patients the primary factor, approximately 50% of kidney transplant patients die of cardiovascular disease. The key factor in causing cardiovascular disease, high blood pressure are grafting and high cholesterol.
Some experts pointed out that six months after kidney transplantation is still 25% to 40% of kidney transplant patients will gradually appear renal dysfunction, proteinuria, progressive renal anemia and other smaller in size and appeared in the 10 years renal failure. Including chronic renal function loss after 6 months to several years after, patients often have no discomfort.
Third, do not for the crowd
Disease patients following renal transplantation should not do: schizophrenia, metastatic tumors, chronic active hepatitis, cirrhosis, chronic obstructive pulmonary disease, bronchiectasis, had disseminated tuberculosis, refractory heart failure, blood coagulation deficiency , nodular nodosa, coccidioidomycosis, acquired immunodeficiency disease, Fabry's disease, primary oxalate urine disease.
Fourth, rejection after kidney transplantation is difficult to avoid
Renal transplant rejection is an immune response, the transplanted kidney was the presence of allogeneic antigen, a kidney transplant the immune system to the allogeneic antigens and humoral immune response cells, the immune response is rejection. According to clinical manifestations, pathology, etc. will be divided into four rejection, its clinical manifestations, mechanisms and prevention methods differ.
Hyperacute rejection: it is usually in the renal blood vessels connected with the receptor within 48 hours, the fastest place in a few minutes. Of hyperacute rejection is currently no effective treatment, once the graft had to be removed, ready to re-transplantation.
Accelerated rejection reaction: occurs 3-5 days after surgery, kidney transplantation showed significant swelling, tenderness, fever patients, oliguria, and high blood pressure, serum creatinine, and white blood cells increased significantly.
Acute rejection: in one week after kidney transplantation, and may coexist with chronic rejection. Patients showed fever, decreased urine output, hypertension, renal tenderness, elevated serum creatinine, and now because of cyclosporin A and other applications, clinical performance has not typical, may be the only change in renal function.
Chronic rejection: generally occurs after six months in renal transplantation, the earliest in three months later. Performance of renal function gradually decreased, with proteinuria or hematuria, blood pressure, slow the disease progress, eventually leading to loss of renal function. Chronic rejection are currently no definite effective treatment.
Fifth, patients must take anti-rejection drugs for life
Rejection of renal transplant patients may face problems at any time. Although the effect of anti-rejection drugs continue to make progress, improve short-term graft survival, but do not have much use for chronic rejection, in the event, the ultimate progressive loss of renal function, need further dialysis. And long-term use of anti-rejection drugs, may reduce the body's immune function, resulting in rejection or infection occurred in patients with causes of death. While the incidence of cancer may be several times normal. Another anti-rejection drugs can cause liver and kidney toxicity, high blood sugar and osteoporosis.
Sixth, the high cost of kidney transplant
The costs of kidney transplantation and the hospital charges, at public expense at their own expense, and other factors, whether the operation successful relationship. Generally goes well, the provincial hospital care, surgery, drugs, treatment, inspection fees, fees, a total of 7-10 million per bed, after the success of anti-rejection drugs needed 3-10 million per year (made the cheap, imported expensive), the dosage must be guaranteed the first year, gradually reduce the dosage. This is an average family can not afford the expenses.