The advantages of minimally invasive treatment of cancer and current situation

1987, Lyon, France, Philipe Mouret with laparoscopic cholecystectomy in the first successful, minimally invasive surgery came into being. Past two decades, minimally invasive surgery means not only getting an unexpected rich and full, the breadth of its scope but also people anticipated. In tumor treatment, minimally invasive surgery is not only used for each stage of cancer treatment, and can complete most of the traditional surgery can accomplish. Although today's minimally invasive surgery can not completely replace traditional surgery, but has in many ways demonstrated its superiority and irreplaceable.

In the process of long-term development of modern surgery, the surgical sector has been the pursuit of a goal is how to treat the disease, based on the procedure itself to minimize harm to patients. To achieve this goal, requires the minimally invasive treatment of tumors in the following two aspects should be as follows: (1) as for therapeutic purposes (radical or palliative), (2) to minimize patient pain (including iatrogenic and disease are the cause of the pain), to maximize the protection of peritumoral normal tissues and organs of the functional integrity and quality of life.

Modern minimally invasive treatment of cancer is broadly divided into the following three areas:

(1) Laparoscopic Surgery

Removal of the tumor using endoscopic techniques have not news, application laparoscopic colon resection, rectal cancer resection, gastric resection, ovarian and uterine tumor resection, and even hepatectomy, pancreaticoduodenectomy, etc. have been There are many reports. Surgical trauma is indeed significantly reduced compared with traditional methods. However, its limitations can not be ignored: the lymph node dissection, tumor-free technology, the integrity of such specimens, have varying degrees of defects. Meanwhile, carbon dioxide laparoscopic surgery pneumoperitoneum and hypercapnia, the pressure of artificial pneumoperitoneum in the respiratory and circulatory effects of pneumoperitoneum on renal hemodynamics, abdominal compartment syndrome and other hazards on the body to be further clarified.

(2) the reform of traditional minimally invasive surgery

In the past to reduce the cancer recurrence rate, expanding the scope of surgical resection, but the last 20 years, people have to expand the trauma of surgery and effect into question. Line of early breast cancer breast-conserving surgery, the treatment effect can be comparable with radical surgery, this has been recognized, its cosmetic effect is radical surgery can not match. Renowned expert Professor Tang Zhaoyou hepatobiliary surgery also suggested the efficacy of local resection liver hepatectomy is effective than 5-year survival rate of up to 64.4%. Liver cirrhosis patients with hepatectomy, some patients died during surgery after the success of liver failure, and the partial removal of the operative mortality rate was significantly lower than the survival time is prolonged. With the longevity of the crowd, accompanied by senior cancer and cardiovascular diseases and other important organs gradually increasing the proportion of patients, many patients can not tolerate traditional surgery, we also need to reform the traditional minimally invasive surgery.

(3) Other:

Interventional therapy, radiofrequency ablation, microwave therapy, focused ultrasound therapy, photodynamic therapy, argon-helium cryoablation, radiation seed implantation and so on. Unlike the former two by the surgeon to implement the method of direct excision of the tumor, a wide variety of such methods, principles, different, but the results are in situ inactivation of the tumor, and by the internal medicine, radiology, ultrasound and other medical departments to implement.

In general, minimally invasive treatment of cancer has the following advantages: (1) trauma, only a small incision in the body surface or no open incision, rapid recovery. (2) partial curative effect. (3) can play a radical role in early cancer, advanced tumors can be achieved by palliative care and other purposes. (4) positioning accuracy, selectivity, to maximize protection of normal tissues and organs function. Because of these many advantages, minimally invasive treatment has become indispensable in comprehensive cancer treatment an important part.

Minimally invasive therapy is a local treatment, in the control and elimination of local lesion, the treatment with chemotherapy and biological means have an absolute advantage in comparison, but it is not a panacea. In practice we can not one-sided pursuit of minimally invasive. Only a matter of fact should be strictly controlled disease, a reasonable selection of appropriate means, and in combination with other effective way to fully reflect the advantages of minimally invasive treatment to improve the therapeutic effect.

Another bone cancer treatment drugs effect

Zoledronic acid is a class of drugs called bisphosphonates a member of the family, these drugs can prevent cancer patients with bone metastases (ie, other parts of the body of tumor metastasis to the bone on) the occurrence of fractures, but these drugs are also used for treatment of osteoporosis.

Previous laboratory studies and animal experiments strongly suggest that zoledronic acid may have anti-tumor effect, these studies suggest that zoledronic acid can inhibit cell proliferation and division, reduce the adhesion between cells have ability to inhibit growth of blood vessels supply the tumor nutrition, also promote tumor growth in immune cells. According to these results, the Austrian Breast and Colorectal Cancer Institute organized the clinical trials, a total of 1801 with early breast cancer in premenopausal women to participate.

All the participants will carry out a breast tumor resection, and taking a drug inhibiting estrogen production in order to induce menopause.

Participants were randomly divided into two groups, one group was injected with zoledronic acid, the other group received hormone therapy (tamoxifen or Arimidex). Tamoxifen inhibition of tumor cells through estrogen receptors, and Arimidex is synthetic estrogen by inhibiting the body's role in clinical trials showed that both drugs can prevent tumor recurrence in early breast cancer.

Each group has a half a placebo for comparison. The study carried out for three years.

Edge breast cancer chemotherapy can be on holiday

In the rare holidays, many people have the right to select their own holiday. But you know, metastatic breast cancer patients nowadays do not need to look "fake" sigh, holiday eating degrees into a lot of pills patients relax, a new method to improve the quality of life.

≠ intravenous chemotherapy, oral chemotherapy for breast cancer patients with a relaxing break

For metastatic breast cancer patients, should adhere to the full course of chemotherapy in order to "eliminate" all of the cancer cells, however, traditional chemotherapy need to travel back and forth the hospital, so do not expect patients to celebrate the National Day.

In fact, intravenous chemotherapy is not the same, with the technology, the advent of new oral chemotherapy so that patients can take pills to go on holiday. But the choice of drugs also has its limitations, we must first good effect, to control the disease, followed by ease of use, travel and will not break, finally, is to give patients the pain at least, only in the road as far as possible adverse drug reactions light, patients can enjoy a vacation like a normal person.

To sum up, the patient can choose to oral chemotherapy capecitabine, which is an efficient, safe, convenient advantage. Play because of its killing effect against tumor cells, less damage to normal cells, so patients in the resort to facilitate the process of taking medications, and does not produce strong side effects. Also, capecitabine is given orally in patients with self-medication at home, on the one hand and effective treatment of disease, on the one hand and improving the quality of life, do both.

Breast cancer patients should pay attention to what holiday?

Breast cancer patients should first consult a doctor, then doctor's advice and select the appropriate physical condition of their own vacation, in the physical conditions permit, a short-distance travel is a good way. But for low body immunity, patients with weak constitution, you can choose to visit family or to entertain their children at home.