2010/11/26

High risk of Down's screening! Friends help you understand the medicine to help!

I am 24.22 years old, weight 52 kg, gestational age 16 weeks 3 days to June 16 this year, after the end of the first day of the month. October 9 Down's screening done.
Examination, AFP 47.2U/ml 1.33
HCG 76.4ng/ml 4.51
Trisomy 21 1 / 170 <1 / 270 low-risk,> 1 / 270 high-risk
Trisomy 18 1 / 100000
NTD screening low-risk
The doctor advised to do amniocentesis


Best answer

Hello:

Overall, the results of Down's screening is normal!
Down through the maternal serum screening for AFP and HCG levels, combined with maternal age, weight, gestational age calculated risk values. Critical value of 1:275. Greater than for the high-risk, low risk, compared with less than. General population (37 years) with Down (DS) of the probability of 1:750.

Down's screening is to check the fetus, and fetal neural tube defects of chromosome examination.
These test results is the computer out of the data. This test project did not achieve the sensitivity and specificity of 100%. We can not completely rely on him to determine the health of the fetus is normal or not, just play a supporting diagnostic examination.
And you better check and calculate the expected date the results of Tang screen. Down 17-20 weeks of pregnancy do recommend screening.
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Trisomy 21 risk value: 1:170 <1 / 270 low-risk,> 1 / 270 high-risk
Fertility 170 meaning that your baby has a Down's baby!

Trisomy 18 risk value: 1:10000
Fortunately, these checks are low risk.

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AFP 47.2

Fetoprotein (AFP) generally range from 0.7-2.5MOM. AFP normal should be greater than 2.5MoM, testing the lower the value, the higher the chance of fetal risk of Down syndrome.
The same test you exclude high-risk high value of 47.2!

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hCG 76.4

hCG is human chorionic gonadotropin, placental syncytiotrophoblast an acidic glycoprotein secreted /. The higher this hormone, the higher the chance of fetal risk of Down syndrome. Some can even reach more than 10,000 pregnant women! So you can accept the result of 76.4!

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uE3 (-)
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NTD screening low-risk

And if you want to continue pregnancy, in amniotic fluid to be done to see if the biopsy.
To be clear, Tang fetal screening examination can help determine the chances of people with Down syndrome, but not clear whether the risk of fetal Down syndrome. That blood test index is high, the cherished "Don" a higher chance of the baby, but does not mean that the fetus must have a problem. On the other hand, even the normal laboratory indices, we can not guarantee the fetus will definitely not sick.

Amniocentesis has some risk, if you do biopsy, must go to the local regular maternal and child health hospital.
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B-only as a supplementary means of a simple B-chromosomes can not see the aspects of the disease,

Micro-ultrasound is recommended that you follow up to see more!
Or extract the amniotic fluid, cultured fetal cells shed in the amniotic fluid to test fetal chromosomes.

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I wish the baby healthy!



Are low-risk, they can do can not do. Down's screening can not be the basis for more accurate amniotic fluid.


High-risk, trisomy 21 1 / 170 high-risk, trisomy 21 is Down's syndrome, amniocentesis as soon as possible to make an appointment. Trisomy 21 1:230 I have an appointment puncture the amniotic fluid. Or do something more comfortable. Birth to a baby is not a problem we can bear. Good luck!