What is encephalitis?

Etiology
The pathogen is a virus family Flaviviridae Phi film is the first sub-group, spherical, diameter 20 ~ 40nm, single-stranded RNA virus, outside the lipid envelope, the surface of hemagglutinin, can agglutinate chicken red blood cells, the virus intracellular proliferation, the temperature, ether, acid, etc. are very sensitive, in suckling mice brain tissue passage, also in the chick embryo, monkey kidney cells, chicken embryo cells and Hela cells such as growth.
Pathogenesis
JE virus infected mosquito bites the human body, the virus first in the local tissue cells and lymph nodes, and vascular endothelial cell proliferation, and constantly invade the bloodstream, the formation of viremia. Disease or not, depending on the number of virus, virulence and immune function, the vast majority of infected people is not the disease, showing latent infection. When the invasion of virus quantity, toxicity and strong immune function is inadequate, the virus continues to multiply, spread the blood line of the body. As a neurotropic virus and it could break through the blood-brain barrier invasion of the central nervous system, especially in low blood-brain barrier or brain parenchyma has been virus are easy to induce the disease.
Found to prevent
Early detection of patients, timely isolation and treatment of patients, but the main source of infection is domestic animals, especially not after the epidemic season of young pigs, young pigs vaccinated in recent years, applications to reduce the herd of viremia, to control the population b brain pop. Mosquito control and mosquito control is an important part of the epidemic, especially for Culex measures. For vaccination is an important measure to protect vulnerable populations, the current use is made of hamster kidney tissue culture inactivated vaccine, the epidemic season testing, protection rate of 60% to 90%. Vaccinated 2 times normal, an interval of 7 to 10; the second year booster shots once. Vaccination of children under the age of 10 and from non-endemic areas into endemic areas of personnel, but high-risk adults should also be considered. Vaccination should be noted: ① triple vaccine at the same time can not be injected with typhoid; ② central nervous system disorders and chronic alcoholism were banned. Was reported after JE vaccination (about 2 weeks) acute disseminated encephalomyelitis, oral prednisolone (2mg/kg · day) quickly restored. Vaccine immunity generally after the second injection of 2 to 3 weeks, 4 to 6 months to maintain, therefore, vaccination should be completed one month before the epidemic.

Is a kind of viral encephalitis is an acute infectious disease, May and June each year, primarily through mosquito bites, the virus into the human body.